Wednesday 24 October 2012

Acne No More Review - Clinical Symptoms of Acne



Clinical Symptoms Of Acne
Acne (acne) is a clinically and heterogeneous group of lesions of the sebaceous glands, which proceeds with the formation of comedones and inflammatory skin problem.
Allocate acne newborn, infant, youth and late. Baby acne occurs during hormonal crisis as a time of hypertrophy of the sebaceous glands and miliums.


Infant acne is observed in children aged 6 months to 2-3 years of age are usually inflammatory in nature and develop against transient disorders of inhibition of endogenous steroids. Later acne appear aged 30-40 years against the pathology of adrenal hyperandrogenism or reproductive glands, which is accompanied by metabolic disorder in sebocytes, increased sensitivity of the receptors to testosterone metabolites, as well as other changes that affect the development of acne.

Teenage acne are found in 80-90% of adolescents. Most of them are 18-20 years to reverse the development of acne, 20% of patients, this process is delayed, and in 1.5% of men and 0.4% of women the disease becomes severe during the formation of the deep scars and pigmentation.



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Factors affecting the development of the youth of acne:
 Violation of the quality and quantity of sebum;
Changes in hormonal status;
Abnormal keratinization of the follicular canal;
Intensive colonization propionbaktery acne sebaceous glands;

Moreover, the symptoms are also indicated with the development of inflammatory reactions in the Perifollicular areas with Genetic predisposition. Quality and quantity of sebum have a significant impact on the development of acne. Sebum lipids consist of two components: the epidermal lipids and lipids are synthesized in the sebaceous glands.

When there is a reduction of the content of epidermal lipids and increased secretion of lipids in the sebaceous glands of the increase in their follicular cholesterol sulfate. The latter enhances the adhesion of corneocytes and largely contributes to a retentive hyperkeratosis, which is the cause of abnormal keratinization mouth sebaceous follicle. When acne occurs as a quantitative change of sebum, which is an important condition for the formation of acne and is often correlated with disease severity of acne.

Secretion of fat depends on many factors: gender, age, temperature, time of day (high and low secretion morning - evening), but mostly it is an indicator of androgenic activity, which results in the future to acne.

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